T-cell lymphoma types include the following:
Adult T-Cell Lymphoma/Leukemia
Anaplastic Large Cell Lymphoma, CD30+
Angioimmunoblastic T-Cell Lymphoma
Cutaneous T-Cell Lymphoma (CTCL)
Enteropathy-type T-Cell Lymphoma
Hepatosplenic T-Cell Lymphoma
Mycosis Fungoides/Sezary Syndrome
Peripheral T-Cell Lymphoma
Subcutaneous panniculitis-like T-Cell Lymphoma
Adult T-Cell Lymphoma/Leukemia
Adult T-cell lymphoma/leukemia occurs when T-cells are infected by the human T-lymphotropic virus. This disease is characterized by circulating malignant T-lymphocytes, skin lesions, enlarged lymph nodes, enlarged liver and spleen, high blood calcium, punched out" bone lesions, and a tendency to infection. This lymphoma may be in an acute, aggressive or chronic, smouldering stage when diagnosed.
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Anaplastic Large Cell Lymphoma, CD30+
Anaplastic large cell lymphoma may be present in an individual in one of two ways: either throughout the body or cutaneous, which is in or on the skin.
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Angioimmunoblastic T-Cell Lymphoma
Angioimmunoblastic lymphoma is an aggressive cancer that is generally characterized by high fever, night sweats, weight loss, skin rash, a positive Coomb’s test (which measures the presence of antibodies to red blood cells in the blood) and possibly swelling of the lymph nodes. Formerly referred to as angioimmunoblastic lymphadenopathy with dysproteinemia (AILD), angioimmunoblastic T-cell lymphoma makes up about 1-2% of all types of Non-Hodgkin's Lymphoma in the United States, and typically occurs in adults ages 40-90 years, mainly males. Learn more about angioimmunoblastic T-cell lymphoma
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Cutaneous T-Cell Lymphoma (CTCL)
Cutaneous T-cell lymphoma is a low grade T-cell lymphoma that generally is noticed in in or on the skin. The most common type of CTCL is mycosis fungoides, which appears on the skin as patches or plaques. In rare cases, affected individuals may develop Sezary syndrome, a leukemic variant. Sézary syndrome (SS) is a more advanced type of CTCL-- a leukemic variant of mycosis fungoides--and is characterized by widespread reddening of the skin. Also, persons with SS will have a red rash over their entire body and have abnormal lymphocytes in the blood stream. As this condition persists, the skin will scale off and become intensely itchy. Learn more about cutaneous T-cell lymphoma
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Enteropathy-type T-Cell Lymphoma
Enteropathy-type T-cell lymphoma is an aggressive intestinal condition that typically occurs in an individual with celiac disease, a disease of the small intestine. In rare instances, this lymphoma may occur in extraintestinal sites.
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Hepatosplenic T-Cell Lymphoma
Hepatosplenic T-cell non-Hodgkin's lymphoma is a rare and aggressive form of Non-Hodgkin’s Lymphoma. Learn more about hepatosplenic T-cell lymphoma.
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Mycosis Fungoides/Sezary Syndrome
Mycosis fungoides is the most common type of cutenous T-cell lymphoma and appears on the skin as patches or plaques. Rarely, mycosis fungoides develops into Sezary syndrome, a leukemic variant. Learn more about mycosis fungoides/Sezary syndrome.
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Peripheral T-Cell Lymphoma
Peripheral T-cell lymphoma is a lymphoma of the T-cells that is first generally characterized by a painless swelling of the neck, armpit or groin, the result of enlarged lymph nodes. Often different organs are affected, such as the bone marrow, liver, spleen, stomach or bowel, and the skin. Some individuals may lose their appetite, feel tired and experience night sweats, fevers and weight loss. Some individuals with this type of lymphoma will already have been diagnosed with other conditions affecting the immune system, or have an overproduction of particular types of blood cells. Learn more about peripheral T-cell lymphoma.
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Subcutaneous panniculitis-like T-Cell Lymphoma
Subcutaneous panniculitis-like T-cell lymphoma is not a common cutaneous lymphoma. Studies of this lymphoma are limited.
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